Superior methylated B-complex for optimal energy, mood, and nervous system support during perimenopause.
B vitamins are the backbone of energy metabolism, nervous system function, and mood regulation - all of which come under pressure during perimenopause. This comprehensive formula delivers all 8 essential B vitamins in their most bioavailable methylated forms, including methylcobalamin (B12), pyridoxal-5-phosphate (B6), and L-5-methyltetrahydrofolate (folate). Plus added Choline, Inositol, and PABA for enhanced nerve transmission and fatty acid metabolism.
Why This Formula
✔ All B vitamins in advanced bioavailable forms - methylated where it matters for maximum absorption
✔ Supports energy-yielding metabolism to combat perimenopause fatigue
✔ Contributes to normal psychological function and mood regulation
✔ Supports normal functioning of the nervous system during hormonal transitions
✔ Added Choline and Inositol for enhanced cognitive and cell-signalling support
✔ Two capsules daily deliver 1800%+ NRV for comprehensive B-complex coverageWho It's For
Active women in perimenopause experiencing fatigue, brain fog, mood changes, or nervous system strain. Ideal if you want a comprehensive B-vitamin formula using premium forms rather than cheap synthetic versions.
Not suitable for children. Consult your healthcare practitioner if pregnant, lactating, or taking medication.
The xSpan Labs Standard
Small-batch manufactured in the UK to GMP and ISO 9001 standards. No unnecessary fillers, no artificial colours, no inflated marketing - just premium-grade ingredients in their most effective forms. Every batch is tested for purity and potency.
Vitamin B Complex - Methylated Energy, Mood & Nervous System Support - 120 Capsu
Directions
Adults take 1 capsule twice daily with food and water. Do not exceed recommended daily dose.
Ingredients
Microcrystalline Cellulose, Capsule Shell: Hydroxypropylmethylcellulose, Niacin (as Nicotinamide), Choline (Choline Bitartrate, Silica), Pantothenic Acid (as D-Calcium Pantothenate), Riboflavin (as Riboflavin 5 Phosphate Sodium), Thiamin (as Thiamin Hydrochloride), Inositol, Para-aminobenzoic acid, Vitamin B6 (as Pyridoxal-5-Phosphate), Anti-Caking Agents: (Magnesium Stearate, Silicon Dioxide), Folic Acid (as L-5-Methyltetrahydrofolate Calcium), Biotin (as D-Biotin), Vitamin B12 (as Methylcobalamin).
Cautions
Always consult your health practitioner before taking nutritional supplements if you are taking medication or are under medical supervision. Pregnant or lactating mothers should consult a health practitioner before using health supplements. You should not take supplements as a substitute for a varied balanced diet. Store in a cool dry place, out of reach of children. Do not exceed stated dose unless under instruction from your health practitioner. Allergies/Intolerances:This product is manufactured in a facility that also handles allergy based materials such as nuts, seeds, milk, egg, cereals, soya, mustard, celery, fish, crustaceans and sulphites.
Suitable for both Vegetarians or Vegans.
xSpan Labs Vitamin B Comprehensive Formula - 90 capsules - Superior Methylated Formula with added Choline, PABA & Inositol - Includes essential multi B-Vitamins B1, B2, B3, B5, B6, B12, Biotin & Folate – 45 day supply - 100% Vegan:
- Vitamin B1 as Thiamine hydrochloride : Thiamine hydrochloride has the advantage of both diffusion and transport absorption. Vitamin B1, thiamin, or thiamine, enables the body to use carbohydrates as energy. It is essential for glucose metabolism, and it plays a key role in nerve, muscle, and heart function
- Vitamin B2 as Riboflavin-5-phosphate :this form of Riboflavin is immediately ready for the body to use without having to be converted
- Vitamin B3 as Nicotinamide : this is the non-flushing form of Niacin. B3 or Niacin is a vitamin that acts as an antioxidant and plays a key role in cell signalling and DNA repair
- Vitamin B5 as Calcium D pantothenate : only the D-pantothenic acid variant is biologically active, whilst the L-pantothenic acid can inhibit the action of the D form . B5 has a key function in neurotransmitter production and is necessary for making blood cells
- Vitamin B6 as Pyridoxal-5-phosphate : Pyridoxal 5-phosphate (P5P) is the active coenzyme form of Vitamin B6 which can be directly utilized by the body without conversion and is a cofactor for more than 150 enzymes in our body . B6 is required for normal hormone, nervous system and blood cell function
- Vitamin B7 as D-Biotin : of the 8 forms of biotin only the natural D-Biotin form has full vitamin activity. B7 supports the health of skin and hair as well as carbohydrate, protein and fat metabolism
- Folate as L-5-methyltetrahydrofolate :5-MTHF requires no additional metabolic steps to be used by the body and is often the preferred choice for those with absorption or metabolic defects. Folate is one of the B-vitamins and is needed to make red and white blood cells in the bone marrow and produce DNA and RNA
- Vitamin B12 as Methylcobalamin : this is the natural form of B12 and is better absorbed and retained within cells than cyanocobalamin. B12 has many roles in the body. It supports the normal function of your nerve cells and is needed for red blood cell formation and DNA synthesis
- Inositol : often referred to as Vitamin B8, inositol is not a vitamin but a type of sugar with several important functions in the body
- Choline as Choline Bitartrate :Choline bitartrate is over 40% choline by weight. This makes it the most choline-rich cholinergic. Choline along with B12 and folate, help with a process that's important for DNA synthesis
- Para-aminobenzoic acid (PABA) : is a natural substance and is sometimes called vitamin Bx


Reviews
This has now become a regular purchase. Good quality methylated B- vitamin formulation, so more bioavailable than many other products. Good value. I was getting cramps and did a blood test expecting my mineral levels to be low. I was quite surprised to discover that it was actually my vitamin B levels that were low. These tablets are easy to swallow, and don’t really have a taste.
So we run in cycles in terms of doing B supplements, but they've become more important recently. This did fine in our rotation.
Price is ok, and tablets are an easy size to swallow. For some reason though, I found that they made me feel a bit nauseous.
I cannot comment on the medical side, but this is a nice combination with dosage that works for me.
My husband was very tired all the time so I thought I would try these. Good value